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thymidylate synthase inhibitor : ウィキペディア英語版
thymidylate synthase inhibitor
Thymidylate synthase inhibitors are chemical agents which inhibit the enzyme thymidylate synthase and have potential as an anticancer chemotherapy. Five agents were in clinical trials in 2002: raltitrexed, pemetrexed, nolatrexed, ZD9331, and GS7904L.
Examples include
* Raltitrexed, used for colorectal cancer since 1998
* Fluorouracil, used for colorectal cancer
* BGC 945
* OSI-7904L
==References==



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